Anti-EDG3 antibody [R01-9K7] (STJA0037363)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human EDG3
General Information
| Short Description | Rabbit monoclonal anti-EDG3 for use in WB, IHC-P, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-9K7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | S1PR3 |
| Gene ID | 1903 |
| Uniprot ID | S1PR3_HUMAN |
| Immunogen | A synthesized peptide derived from human EDG3 |
Additional Info
| Tissue Specificity | Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver. |
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
| Protein Name | Sphingosine 1-Phosphate Receptor 3S1p Receptor 3S1p3Endothelial Differentiation G-Protein Coupled Receptor 3Sphingosine 1-Phosphate Receptor Edg-3S1p Receptor Edg-3 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419408Reactome: R-HSA-9009391 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 3 antibodyAnti-S1p Receptor 3 antibodyAnti-S1p3 antibodyAnti-Endothelial Differentiation G-Protein Coupled Receptor 3 antibodyAnti-Sphingosine 1-Phosphate Receptor Edg-3 antibodyAnti-S1p Receptor Edg-3 antibodyAnti-S1PR3 antibodyAnti-C9orf108 antibodyAnti-C9orf47 antibodyAnti-EDG3 antibody |
Information sourced from Uniprot.org