Anti-EDC3 antibody (159-508) (STJ115710)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal EDC3 (159-508) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EDC3 |
| Gene ID | 80153 |
| Uniprot ID | EDC3_HUMAN |
| Immunogen Region | 159-508 |
| Immunogen Sequence | HNSWSSSSRHPNQATPKKSG LKNGQMKNKDDECFGDDIEE IPDTDFDFEGNLALFDKAAV FEEIDTYERRSGTRSRGIPN ERPTRYRHDENILESEPIVY RRIIVPHNVSKEFCTDSGLV VPSISYELHKKLLSVAEKHG LTLERRLEMTGVCASQMALT LLGGPNRLNPKNVHQRPTVA LLCGPHVKGAQGISCGRHLA NHDVQVILFLPNFVKMLESI TNELSLFSKTQGQQVSSLK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 159-508 of human EDC3 (NP_079359.2). |
Additional Info
| Tissue Specificity | Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland. |
| Function | Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping. May play a role in spermiogenesis and oogenesis. |
| Protein Name | Enhancer Of Mrna-Decapping Protein 3Lsm16 HomologYjef N-Terminal Domain-Containing Protein 2Yjef_n2Hyjef_n2Yjef Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-430039 |
| Cellular Localisation | CytoplasmP-BodyProcessing Bodies (Pb) |
| Alternative Antibody Names | Anti-Enhancer Of Mrna-Decapping Protein 3 antibodyAnti-Lsm16 Homolog antibodyAnti-Yjef N-Terminal Domain-Containing Protein 2 antibodyAnti-Yjef_n2 antibodyAnti-Hyjef_n2 antibodyAnti-Yjef Domain-Containing Protein 1 antibodyAnti-EDC3 antibodyAnti-LSM16 antibodyAnti-YJDC antibodyAnti-YJEFN2 antibodyAnti-PP844 antibody |
Information sourced from Uniprot.org