Anti-ECSCR antibody [SAA1685] (STJA0020113)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Endothelial Cell-Specific Chemotaxis Regulator antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1685 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | ECSCR |
| Gene ID | 641700 |
| Uniprot ID | ECSCR_HUMAN |
Additional Info
| Post Translational Modifications | May be heavily O-glycosylated. |
| Function | Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. |
| Protein Name | Endothelial Cell-Specific Chemotaxis RegulatorApoptosis Regulator Through Modulating Iap ExpressionAriaEndothelial Cell-Specific Molecule 2 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Endothelial Cell-Specific Chemotaxis Regulator antibodyAnti-Apoptosis Regulator Through Modulating Iap Expression antibodyAnti-Aria antibodyAnti-Endothelial Cell-Specific Molecule 2 antibodyAnti-ECSCR antibodyAnti-ECSM2 antibody |
Information sourced from Uniprot.org