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Anti-EBV-EA-p50-55 antibody [1108-1] (STJ16100758)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA BALB/c mouse was immunized with immunoprecipitated EBV early antigens. Fusion partner: NS-0.
General Information
| Short Description | Mouse monoclonal anti-EBV-EA-p50-55 for use in FC, IF, IHC and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1108-1 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30-60 minutes at RT; for staining of formalin-fixed tissues no suitable antigen retrieval method is known to date). Immunopre |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8°C upon receipt. |
Target Information
| Gene Symbol | HCN3 |
| Gene ID | 57657 |
| Uniprot ID | HCN3_HUMAN |
| Immunogen | A BALB/c mouse was immunized with immunoprecipitated EBV early antigens. Fusion partner: NS-0. |
Additional Info
| Tissue Specificity | Detected in brain. |
| Function | Hyperpolarization-activated ion channel that are permeable to sodium and potassium ions, with an about 3:1 preference for potassium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). In particular, plays a pivotal role in maintaining excitability and promoting rhythmic burst firing within hypothalamic nuclei. Exerts a significant influence on the configuration of the cardiac action potential waveform. Does not appear to play a prominent role in the processing of acute, neuropathic, or inflammatory pain. |
| Protein Name | Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 |
| Database Links | Reactome: R-HSA-1296061 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 antibodyAnti-HCN3 antibodyAnti-KIAA1535 antibody |
Information sourced from Uniprot.org