• STJ72935 (2µg/ml) staining of Human Hippocampus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-EAAT1/GLAST1 antibody (C-Term) (STJ72935)

SKU:
STJ72935-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-EAAT1/GLAST1 (C-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:8000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SLC1A3
Gene ID: 6507
Uniprot ID: EAA1_HUMAN
Immunogen Region: C-Term
Accession Number: NP_004163.3; NP_001160167.1
Specificity: This antibody is expected to recognize isoform 1 (NP_004163.3) and isoform 2 (NP_001160167.1).
Immunogen Sequence: DNETEKPIDSETK
Post Translational Modifications Glycosylated.
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate.
Protein Name Excitatory Amino Acid Transporter 1
Sodium-Dependent Glutamate/Aspartate Transporter 1
Glast-1
Solute Carrier Family 1 Member 3
Database Links Reactome: R-HSA-210455
Reactome: R-HSA-210500
Reactome: R-HSA-425393
Reactome: R-HSA-5619062
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Excitatory Amino Acid Transporter 1 antibody
Anti-Sodium-Dependent Glutamate/Aspartate Transporter 1 antibody
Anti-Glast-1 antibody
Anti-Solute Carrier Family 1 Member 3 antibody
Anti-SLC1A3 antibody
Anti-EAAT1 antibody
Anti-GLAST antibody
Anti-GLAST1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance