• Immunohistochemistry analysis of paraffin-embedded rat kidney using DYNC1LI2 Rabbit polyclonal antibody (STJ11103393) at dilution of 1:20 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using DYNC1LI2 Rabbit polyclonal antibody (STJ11103393) at dilution of 1:20 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using DYNC1LI2 Rabbit polyclonal antibody (STJ11103393) at dilution of 1:20 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using DYNC1LI2 Rabbit polyclonal antibody (STJ11103393) at dilution of 1:20 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using DYNC1LI2 antibody (STJ11103393) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-DYNC1LI2 antibody (328-492) (STJ11103393)

SKU:
STJ11103393

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DYNC1LI2 (328-492) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DYNC1LI2
Gene ID: 1783
Uniprot ID: DC1L2_HUMAN
Immunogen Region: 328-492
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 328-492 of human DYNC1LI2 (NP_006132.1).
Immunogen Sequence: TTVKPEDAYEDFIVKPPVRK LVHDKELAAEDEQVFLMKQQ SLLAKQPATPTRASESPARG PSGSPRTQGRGGPASVPSSS PGTSVKKPDPNIKNNAASEG VLASFFNSLLSKKTGSPGSP GAGGVQSTAKKSGQKTVLSN VQEELDRMTRKPDSMVTNSS TENEA
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
Protein Name Cytoplasmic Dynein 1 Light Intermediate Chain 2
Dynein Light Intermediate Chain 2 - Cytosolic
Lic-2
Lic53/55
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-2132295
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-3371497
Reactome: R-HSA-5663220
Reactome: R-HSA-6807878
Reactome: R-HSA-6811436
Reactome: R-HSA-68877
Reactome: R-HSA-9609690
Reactome: R-HSA-9646399
Reactome: R-HSA-9648025
Cellular Localisation Cytoplasm
Cytoskeleton
Alternative Antibody Names Anti-Cytoplasmic Dynein 1 Light Intermediate Chain 2 antibody
Anti-Dynein Light Intermediate Chain 2 - Cytosolic antibody
Anti-Lic-2 antibody
Anti-Lic53/55 antibody
Anti-DYNC1LI2 antibody
Anti-DNCLI2 antibody
Anti-LIC2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance