Anti-DUSP7 antibody (210-260 aa) (STJ195937)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human DUS7 at the amino acid range 210-260
General Information
| Short Description | Rabbit polyclonal anti-Dual specificity protein phosphatase 7 (210-260 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DUSP7 |
| Gene ID | 1849 |
| Uniprot ID | DUS7_HUMAN |
| Immunogen | Synthesized peptide derived from the human DUS7 at the amino acid range 210-260 |
| Immunogen Region | 210-260 aa |
| Specificity | This antibody detects endogenous levels of DUS7 at Human/Mouse/Rat |
Additional Info
| Function | Dual specificity protein phosphatase. Shows high activity towards MAPK1/ERK2. Also has lower activity towards MAPK14 and MAPK8. In arrested oocytes, plays a role in meiotic resumption. Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in oocytes, probably by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB. May also inactivate PRKCA and/or PRKCG. Also important in oocytes for normal chromosome alignment on the metaphase plate and progression to anaphase, where it might regulate activity of the spindle-assembly checkpoint (SAC) complex. |
| Protein Name | Dual Specificity Protein Phosphatase 7Dual Specificity Protein Phosphatase Pyst2 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-202670Reactome: R-HSA-5675221Reactome: R-HSA-9652817 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 7 antibodyAnti-Dual Specificity Protein Phosphatase Pyst2 antibodyAnti-DUSP7 antibodyAnti-PYST2 antibody |
Information sourced from Uniprot.org