Anti-DUSP4 antibody [IHC491] (STJA0042160)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
General Information
| Short Description | Mouse monoclonal anti-DUSP4 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-p |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | IHC491 |
| Conjugation | Unconjugated |
| Formulation | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1 year. Do not freeze. |
Target Information
| Gene Symbol | DUSP4 |
| Gene ID | 1846 |
| Uniprot ID | DUS4_HUMAN |
| Specificity | Tested and validated on liver cancer tissue. |
Additional Info
| Post Translational Modifications | Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein. |
| Function | Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. |
| Protein Name | Dual Specificity Protein Phosphatase 4Dual Specificity Protein Phosphatase Hvh2Mitogen-Activated Protein Kinase Phosphatase 2Map Kinase Phosphatase 2Mkp-2 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-202670Reactome: R-HSA-5675221 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 4 antibodyAnti-Dual Specificity Protein Phosphatase Hvh2 antibodyAnti-Mitogen-Activated Protein Kinase Phosphatase 2 antibodyAnti-Map Kinase Phosphatase 2 antibodyAnti-Mkp-2 antibodyAnti-DUSP4 antibodyAnti-MKP2 antibodyAnti-VH2 antibody |
Information sourced from Uniprot.org