| Short Description : | Rabbit polyclonal anti-DUET for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:1000-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KALRN |
| Gene ID: | 8997 |
| Uniprot ID: | KALRN_HUMAN |
| Immunogen: | Synthesized peptide derived from human DUET |
| Specificity: | This antibody detects endogenous levels of Human DUET |
| Post Translational Modifications | Autophosphorylated. |
| Function | Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity. |
| Protein Name | KalirinHuntingtin-Associated Protein-Interacting ProteinProtein DuoSerine/Threonine-Protein Kinase With Dbl- And Pleckstrin Homology Domain |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-3928662Reactome: R-HSA-416476Reactome: R-HSA-416482Reactome: R-HSA-5687128Reactome: R-HSA-8980692Reactome: R-HSA-9013149Reactome: R-HSA-9013408 |
| Cellular Localisation | CytoplasmCytoskeletonAssociated With The Cytoskeleton |
| Alternative Antibody Names | Anti-Kalirin antibodyAnti-Huntingtin-Associated Protein-Interacting Protein antibodyAnti-Protein Duo antibodyAnti-Serine/Threonine-Protein Kinase With Dbl- And Pleckstrin Homology Domain antibodyAnti-KALRN antibodyAnti-DUET antibodyAnti-DUO antibodyAnti-HAPIP antibodyAnti-TRAD antibody |
Information sourced from Uniprot.org
