Anti-DTNA antibody (STJA0037485)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenPeptide
General Information
| Short Description | Rabbit monoclonal anti-DTNA for use in WB, IHC-F, IHC-P, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB-1:1000-1:5000IHC-P-1:50-1:100ICC/IF-1:100-1:200FC-1:50-1:100 |
| Formulation | Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DTNA |
| Gene ID | 1837 |
| Uniprot ID | DTNA_HUMAN |
| Immunogen | Peptide |
Additional Info
| Tissue Specificity | Highly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas. Isoform 2 is not expressed in cardiac muscle. Isoform 7 and isoform 8 are only expressed in muscle. |
| Post Translational Modifications | Phosphorylation of DTN-1 on tyrosine kinase substrate domain present in the C-terminus. |
| Function | May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. |
| Protein Name | Dystrobrevin AlphaDtn-AAlpha-DystrobrevinDystrophin-Related Protein 3 |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | CytoplasmSynapseCell MembraneIn Peripheral NervesColocalizes With Magee1 In The Schwann Cell Membrane |
| Alternative Antibody Names | Anti-Dystrobrevin Alpha antibodyAnti-Dtn-A antibodyAnti-Alpha-Dystrobrevin antibodyAnti-Dystrophin-Related Protein 3 antibodyAnti-DTNA antibodyAnti-DRP3 antibody |
Information sourced from Uniprot.org