Anti-DTNA antibody (131-181 aa) (STJ194823)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human DTNA at the amino acid range 131-181
General Information
| Short Description | Rabbit polyclonal anti-Dystrobrevin alpha (131-181 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DTNA |
| Gene ID | 1837 |
| Uniprot ID | DTNA_HUMAN |
| Immunogen | Synthesized peptide derived from the human DTNA at the amino acid range 131-181 |
| Immunogen Region | 131-181 aa |
| Specificity | This antibody detects endogenous levels of DTNA at Human/Mouse |
Additional Info
| Post Translational Modifications | Phosphorylation of DTN-1 on tyrosine kinase substrate domain present in the C-terminus. |
| Function | May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. |
| Protein Name | Dystrobrevin AlphaDtn-AAlpha-DystrobrevinDystrophin-Related Protein 3 |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | CytoplasmSynapseCell MembraneIn Peripheral NervesColocalizes With Magee1 In The Schwann Cell Membrane |
| Alternative Antibody Names | Anti-Dystrobrevin Alpha antibodyAnti-Dtn-A antibodyAnti-Alpha-Dystrobrevin antibodyAnti-Dystrophin-Related Protein 3 antibodyAnti-DTNA antibodyAnti-DRP3 antibody |
Information sourced from Uniprot.org