Anti-DSTYK antibody (STJA0007657)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RIPK5
General Information
| Short Description | Rabbit polyclonal anti-Dual serine/threonine and tyrosine protein kinase for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DSTYK |
| Gene ID | 25778 |
| Uniprot ID | DUSTY_HUMAN |
| Immunogen | Synthesized peptide derived from human RIPK5 |
| Specificity | This antibody detects endogenous levels of RIPK5 at Human, Mouse, Rat |
Additional Info
| Function | Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. |
| Protein Name | Dual Serine/Threonine And Tyrosine Protein KinaseDusty Protein KinaseDusty PkRip-Homologous KinaseReceptor-Interacting Serine/Threonine-Protein Kinase 5Sugen Kinase 496Sgk496 |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneApical Cell MembraneBasolateral Cell MembraneCell JunctionDetected At Apical Cell-Cell JunctionsColocalized With Fgf Receptors To The Cell MembraneDetected In Basolateral And Apical Membranes Of All Tubular Epithelia |
| Alternative Antibody Names | Anti-Dual Serine/Threonine And Tyrosine Protein Kinase antibodyAnti-Dusty Protein Kinase antibodyAnti-Dusty Pk antibodyAnti-Rip-Homologous Kinase antibodyAnti-Receptor-Interacting Serine/Threonine-Protein Kinase 5 antibodyAnti-Sugen Kinase 496 antibodyAnti-Sgk496 antibodyAnti-DSTYK antibodyAnti-KIAA0472 antibodyAnti-RIP5 antibodyAnti-RIPK5 antibodyAnti-SGK496 antibodyAnti-HDCMD38P antibody |
Information sourced from Uniprot.org