| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Desmoglein-2 (401-450 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DSG2 |
| Gene ID: | 1829 |
| Uniprot ID: | DSG2_HUMAN |
| Immunogen Region: | 401-450 aa |
| Specificity: | Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DSG2 at the amino acid range 401-450 |
| Post Translational Modifications | Palmitoylated by ZDHHC5 at the plasma membrane. |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Protein Name | Desmoglein-2Cadherin Family Member 5Hdgc |
| Database Links | Reactome: R-HSA-351906Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9013404Reactome: R-HSA-9013408Reactome: R-HSA-9013423 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
| Alternative Antibody Names | Anti-Desmoglein-2 antibodyAnti-Cadherin Family Member 5 antibodyAnti-Hdgc antibodyAnti-DSG2 antibodyAnti-CDHF5 antibody |
Information sourced from Uniprot.org
