Anti-DSCAML1 antibody (STJ192060)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Cell adhesion molecule DSCAML1 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DSCAML1 |
| Gene ID | 57453 |
| Uniprot ID | DSCL1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | DSCL1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells. Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions. |
| Protein Name | Cell Adhesion Molecule Dscaml1Down Syndrome Cell Adhesion Molecule 2Down Syndrome Cell Adhesion Molecule-Like Protein 1 |
| Database Links | Reactome: R-HSA-376172 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynapse |
| Alternative Antibody Names | Anti-Cell Adhesion Molecule Dscaml1 antibodyAnti-Down Syndrome Cell Adhesion Molecule 2 antibodyAnti-Down Syndrome Cell Adhesion Molecule-Like Protein 1 antibodyAnti-DSCAML1 antibodyAnti-DSCAM2 antibodyAnti-KIAA1132 antibody |
Information sourced from Uniprot.org