Anti-DRP2 antibody (437-487 aa) (STJ193705)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human DRP2 at the amino acid range 437-487
General Information
| Short Description | Rabbit polyclonal anti-Dystrophin-related protein 2 (437-487 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DRP2 |
| Gene ID | 1821 |
| Uniprot ID | DRP2_HUMAN |
| Immunogen | Synthesized peptide derived from the human DRP2 at the amino acid range 437-487 |
| Immunogen Region | 437-487 aa |
| Specificity | This antibody detects endogenous levels of DRP2 at Human/Mouse/Rat |
Additional Info
| Function | Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells. Required for normal PRX location at appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane. Possibly involved in membrane-cytoskeleton interactions of the central nervous system. |
| Protein Name | Dystrophin-Related Protein 2Drp-2 |
| Database Links | Reactome: R-HSA-9619665Reactome: R-HSA-9913351 |
| Cellular Localisation | Postsynaptic DensityCell ProjectionDendritePerikaryonCell MembranePeripheral Membrane ProteinDetected In Schwann Cells At Periaxonal Myelin Membranes |
| Alternative Antibody Names | Anti-Dystrophin-Related Protein 2 antibodyAnti-Drp-2 antibodyAnti-DRP2 antibody |
Information sourced from Uniprot.org