| Host: |
Rabbit |
| Applications: |
CM/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DRD2 is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Biotin |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.55µg/µl |
| Dilution Range: |
WB: 1:1, 000-1:1, 5000ELISA: 1:50, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
DRD2 |
| Gene ID: |
1813 |
| Uniprot ID: |
DRD2_HUMAN |
| Immunogen: |
Synthetic peptide corresponding to unique sequence on human Dopamine D2 Receptor protein. |
| Tissue Specificity | Isoform 1: Expressed in the anterior pituitary gland. Isoform 2: Expressed in the anterior pituitary gland. |
| Post Translational Modifications | Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8. |
| Function | Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5. |
| Protein Name | D(2 Dopamine ReceptorDopamine D2 Receptor |
| Database Links | Reactome: R-HSA-390651 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-D(2 Dopamine Receptor antibodyAnti-Dopamine D2 Receptor antibodyAnti-DRD2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
