Anti-DRAM2 antibody (200-267 aa) (STJ13101054)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 200-267 of mouse DRAM2 conjugated to blue carrier protein has been used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-DRAM2 (200-267 aa) for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. Use at a dilution of 1:200 to 1:2000. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Dram2 |
| Gene ID | 67171 |
| Uniprot ID | DRAM2_MOUSE |
| Immunogen | A synthetic peptide from aa region 200-267 of mouse DRAM2 conjugated to blue carrier protein has been used as the antigen. |
| Immunogen Region | 200-267 aa |
| Specificity | Specific for DRAM2. |
Additional Info
| Function | Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1. |
| Protein Name | Dna Damage-Regulated Autophagy Modulator Protein 2Transmembrane Protein 77 |
| Database Links | |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinPhotoreceptor Inner SegmentApical Cell MembraneLocalized To Photoreceptor Inner Segments And To The Apical Surface Of Retinal Pigment Epithelial Cells |
| Alternative Antibody Names | Anti-Dna Damage-Regulated Autophagy Modulator Protein 2 antibodyAnti-Transmembrane Protein 77 antibodyAnti-Dram2 antibodyAnti-Tmem77 antibody |
Information sourced from Uniprot.org