| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-DRAK2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000. WB: Approx 45kDa band observed in lysates of cell line MOLT4 (calculated MW of 42.3kDa according to NP_004217.1). Recommended concentration: 1-3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | STK17B |
| Gene ID: | 9262 |
| Uniprot ID: | ST17B_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_004217.1 |
| Specificity: | This antiboyd may cross-react with rat STK17B (GeneID: 170904). |
| Immunogen Sequence: | HSVRSSEDKTSK |
| Post Translational Modifications | Autophosphorylated. |
| Function | Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis. |
| Protein Name | Serine/Threonine-Protein Kinase 17b Dap Kinase-Related Apoptosis-Inducing Protein Kinase 2 |
| Cellular Localisation | Nucleus Cell Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Colocalizes With Stk17b At The Plasma Membrane |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase 17b antibody Anti-Dap Kinase-Related Apoptosis-Inducing Protein Kinase 2 antibody Anti-STK17B antibody Anti-DRAK2 antibody |
Information sourced from Uniprot.org
