Western blot analysis of various lysates using DPYSL3 Rabbit polyclonal antibody (STJ114169) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.

Anti-DPYSL3 antibody (440-520) (STJ114169)

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STJ114169
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Applications:WB/ELISA
Host:Rabbit
Reactivity:Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:DPYSL3
Gene ID:1809
Uniprot ID:DPYL3_HUMAN
Immunogen Region:440-520
Immunogen Sequence:RGAPLVVICQGKIMLEDGNL HVTQGAGRFIPCSPFSDYVY KRIKARRKMADLHAVPRGMY DGPVFDLTTTPKGGTPAGSA R
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 440-520 of human DPYSL3 (NP_001378.1).
Tissue Specificity Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
Post Translational Modifications Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.
Function Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Protein Name Dihydropyrimidinase-Related Protein 3
Drp-3
Collapsin Response Mediator Protein 4
Crmp-4
Unc-33-Like Phosphoprotein 1
Ulip-1
Database Links Reactome: R-HSA-399956
Cellular Localisation Cytoplasm
Cell Projection
Growth Cone
Colocalizes With Synaptic Vesicle Protein 2 In The Central Region Of The Growth Cone
Alternative Antibody Names Anti-Dihydropyrimidinase-Related Protein 3 antibody
Anti-Drp-3 antibody
Anti-Collapsin Response Mediator Protein 4 antibody
Anti-Crmp-4 antibody
Anti-Unc-33-Like Phosphoprotein 1 antibody
Anti-Ulip-1 antibody
Anti-DPYSL3 antibody
Anti-CRMP4 antibody
Anti-DRP3 antibody
Anti-ULIP antibody
Anti-ULIP1 antibody

Information sourced from Uniprot.org

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