Anti-DPYSL3 antibody (240-290 aa) (STJ193639)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human DPYL3 at the amino acid range 240-290
General Information
| Short Description | Rabbit polyclonal anti-Dihydropyrimidinase-related protein 3 (240-290 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DPYSL3 |
| Gene ID | 1809 |
| Uniprot ID | DPYL3_HUMAN |
| Immunogen | Synthesized peptide derived from the human DPYL3 at the amino acid range 240-290 |
| Immunogen Region | 240-290 aa |
| Specificity | This antibody detects endogenous levels of DPYL3 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3. |
| Function | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. |
| Protein Name | Dihydropyrimidinase-Related Protein 3Drp-3Collapsin Response Mediator Protein 4Crmp-4Unc-33-Like Phosphoprotein 1Ulip-1 |
| Database Links | Reactome: R-HSA-399956 |
| Cellular Localisation | CytoplasmCell ProjectionGrowth ConeColocalizes With Synaptic Vesicle Protein 2 In The Central Region Of The Growth Cone |
| Alternative Antibody Names | Anti-Dihydropyrimidinase-Related Protein 3 antibodyAnti-Drp-3 antibodyAnti-Collapsin Response Mediator Protein 4 antibodyAnti-Crmp-4 antibodyAnti-Unc-33-Like Phosphoprotein 1 antibodyAnti-Ulip-1 antibodyAnti-DPYSL3 antibodyAnti-CRMP4 antibodyAnti-DRP3 antibodyAnti-ULIP antibodyAnti-ULIP1 antibody |
Information sourced from Uniprot.org