• Western blot analysis of extracts of various cell lines, using DPYS antibody (STJ28451) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-DPYS antibody (250-519) (STJ28451)

SKU:
STJ28451

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DPYS (250-519) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DPYS
Gene ID: 1807
Uniprot ID: DPYS_HUMAN
Immunogen Region: 250-519
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-519 of human DPYS (NP_001376.1).
Immunogen Sequence: MSKSAAKVIADARRDGKVVY GEPIAASLGTDGTHYWNKEW HHAAHHVMGPPLRPDPSTPD FLMNLLANDDLTTTGTDNCT FNTCQKALGKDDFTKIPNGV NGVEDRMSVIWEKGVHSGKM DENRFVAVTSTNAAKIFNLY PRKGRIAVGSDADIVIWDPK GTRTISAKTHHQAVNFNIFE GMVCHGVPLVTISRGKVVYE AGVFSVTAGDGKFIPRKPFA EYIYKRIKQRDRTCTPTPV
Tissue Specificity Liver and kidney.
Post Translational Modifications Carboxylation allows a single lysine to coordinate two zinc ions.
Function Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.
Protein Name Dihydropyrimidinase
Dhp
Dhpase
Dihydropyrimidine Amidohydrolase
Hydantoinase
Database Links Reactome: R-HSA-73621
Alternative Antibody Names Anti-Dihydropyrimidinase antibody
Anti-Dhp antibody
Anti-Dhpase antibody
Anti-Dihydropyrimidine Amidohydrolase antibody
Anti-Hydantoinase antibody
Anti-DPYS antibody

Information sourced from Uniprot.org

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