Anti-DPYS antibody (250-519) (STJ28451)

Name: Anti-DPYS antibody (250-519) (STJ28451)
SKU: STJ28451
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ28451

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Short Description	Rabbit polyclonal DPYS (250-519) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	DPYS
Gene ID	1807
Uniprot ID	DPYS_HUMAN
Immunogen Region	250-519
Immunogen Sequence	MSKSAAKVIADARRDGKVVY GEPIAASLGTDGTHYWNKEW HHAAHHVMGPPLRPDPSTPD FLMNLLANDDLTTTGTDNCT FNTCQKALGKDDFTKIPNGV NGVEDRMSVIWEKGVHSGKM DENRFVAVTSTNAAKIFNLY PRKGRIAVGSDADIVIWDPK GTRTISAKTHHQAVNFNIFE GMVCHGVPLVTISRGKVVYE AGVFSVTAGDGKFIPRKPFA EYIYKRIKQRDRTCTPTPV
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 250-519 of human DPYS (NP_001376.1).

Tissue Specificity	Liver and kidney.
Post Translational Modifications	Carboxylation allows a single lysine to coordinate two zinc ions.
Function	Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.
Protein Name	Dihydropyrimidinase Dhp Dhpase Dihydropyrimidine Amidohydrolase Hydantoinase
Database Links	Reactome: R-HSA-73621
Cellular Localisation
Alternative Antibody Names	Anti-Dihydropyrimidinase antibody Anti-Dhp antibody Anti-Dhpase antibody Anti-Dihydropyrimidine Amidohydrolase antibody Anti-Hydantoinase antibody Anti-DPYS antibody

Information sourced from Uniprot.org