| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DPYD (1-173) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DPYD |
| Gene ID: |
1806 |
| Uniprot ID: |
DPYD_HUMAN |
| Immunogen Region: |
1-173 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human DPYD (NP_000101.2). |
| Immunogen Sequence: |
MAPVLSKDSADIESILALNP RTQTHATLCSTSAKKLDKKH WKRNPDKNCFNCEKLENNFD DIKHTTLGERGALREAMRCL KCADAPCQKSCPTNLDIKSF ITSIANKNYYGAAKMIFSDN PLGLTCGMVCPTSDLCVGGC NLYATEEGPINIGGLQQFAT ETLILAFSLMNHL |
| Tissue Specificity | Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells. |
| Function | Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. |
| Protein Name | Dihydropyrimidine Dehydrogenase Nadp(+DhpdhaseDpdDihydrothymine DehydrogenaseDihydrouracil Dehydrogenase |
| Database Links | Reactome: R-HSA-73621 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Dihydropyrimidine Dehydrogenase Nadp(+ antibodyAnti-Dhpdhase antibodyAnti-Dpd antibodyAnti-Dihydrothymine Dehydrogenase antibodyAnti-Dihydrouracil Dehydrogenase antibodyAnti-DPYD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
