Anti-DPEP1/MDP antibody (STJA0037904)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human DPEP1
General Information
| Short Description | Rabbit monoclonal anti-DPEP1/MDP for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DPEP1 |
| Gene ID | 1800 |
| Uniprot ID | DPEP1_HUMAN |
| Immunogen | A synthesized peptide derived from human DPEP1 |
Additional Info
| Tissue Specificity | Expressed in lung and kidneys. |
| Function | Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Also possesses beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem. Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver. |
| Protein Name | Dipeptidase 1Beta-LactamaseDehydropeptidase-IMicrosomal DipeptidaseRenal DipeptidaseHrdp |
| Database Links | Reactome: R-HSA-2142691Reactome: R-HSA-5423646Reactome: R-HSA-9664535 |
| Cellular Localisation | Apical Cell MembraneLipid-AnchorGpi-AnchorCell ProjectionMicrovillus MembraneBrush Border Membrane |
| Alternative Antibody Names | Anti-Dipeptidase 1 antibodyAnti-Beta-Lactamase antibodyAnti-Dehydropeptidase-I antibodyAnti-Microsomal Dipeptidase antibodyAnti-Renal Dipeptidase antibodyAnti-Hrdp antibodyAnti-DPEP1 antibodyAnti-MDP antibodyAnti-RDP antibody |
Information sourced from Uniprot.org