Anti-Dopamine Receptor D3 antibody [R04-5P5] (STJA0036799)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Dopamine Receptor D3
General Information
| Short Description | Rabbit monoclonal anti-Dopamine Receptor D3 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-5P5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DRD3 |
| Gene ID | 1814 |
| Uniprot ID | DRD3_HUMAN |
| Immunogen | A synthesized peptide derived from human Dopamine Receptor D3 |
Additional Info
| Tissue Specificity | Brain. |
| Post Translational Modifications | Phosphorylated by GRK4 (GRK4-alpha and GRK4-gamma). Palmitoylated. |
| Function | Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation. |
| Protein Name | D(3 Dopamine ReceptorDopamine D3 Receptor |
| Database Links | Reactome: R-HSA-390651Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBoth Membrane-Bound And Scattered In The Cytoplasm During Basal ConditionsReceptor Stimulation Results In The Rapid Internalization And Sequestration Of The Receptors At The Perinuclear Area (5 And 15 Minutes)Followed By The Dispersal Of The Receptors To The Membrane (30 Minutes)Drd3 And Grk4 Co-Localize In Lipid Rafts Of Renal Proximal Tubule Cells |
| Alternative Antibody Names | Anti-D(3 Dopamine Receptor antibodyAnti-Dopamine D3 Receptor antibodyAnti-DRD3 antibody |
Information sourced from Uniprot.org