Anti-Dopamine Beta-Hydroxylase antibody (C-Term) (STJA0003614)

Name: Anti-Dopamine Beta-Hydroxylase antibody (C-Term) (STJA0003614)
SKU: STJA0003614-100
Price: 488.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostSheep

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

STJA0003614-100

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Short Description	Sheep polyclonal anti-Dopamine beta-Hydroxylase (C-Term) for use in WB in Human, Mouse and Non-Human Primates samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB
Host	Sheep
Reactivity	Human/Mouse/Non-Human Primates
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Purification	This antibody was antigen affinity purified from pooled serum.
Dilution Range	WB 1:1000
Formulation	100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	DBH
Gene ID	1621
Uniprot ID	DOPO_HUMAN
Immunogen	Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Immunogen Region	C-Term

Post Translational Modifications	N-glycosylated. Proteolytic cleavage after the membrane-anchor leads to the release of the soluble form.
Function	Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters.
Protein Name	Dopamine Beta-Hydroxylase Dopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase
Database Links	Reactome: R-HSA-209905
Cellular Localisation	Soluble Dopamine Beta-Hydroxylase: Cytoplasmic Vesicle Secretory Vesicle Lumen Cytoplasmic Vesicle Secretory Vesicle Chromaffin Granule Lumen Secreted Secretory Vesicle Membrane Single-Pass Type Ii Membrane Protein Chromaffin Granule Membrane
Alternative Antibody Names	Anti-Dopamine Beta-Hydroxylase antibody Anti-Dopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase antibody Anti-DBH antibody

Information sourced from Uniprot.org