Anti-Dopamine beta hydroxylase antibody (125-178) {Biotin} (STJ507831)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 125-178 on mouse Dopamine beta hydroxylase.
General Information
| Short Description | Rabbit polyclonal antibody anti-Dopamine beta hydroxylase (125-178) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Purification | Affinity Purified |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Dbh |
| Gene ID | 13166 |
| Uniprot ID | DOPO_MOUSE |
| Immunogen | Synthetic peptide taken within amino acid region 125-178 on mouse Dopamine beta hydroxylase. |
| Immunogen Region | 125-178 |
Additional Info
| Post Translational Modifications | Proteolytic cleavage after the membrane-anchor leads to the release of the soluble form. N-glycosylated. |
| Function | Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters. |
| Protein Name | Dopamine Beta-HydroxylaseDopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase |
| Database Links | Reactome: R-MMU-209905 |
| Cellular Localisation | Soluble Dopamine Beta-Hydroxylase: Cytoplasmic VesicleSecretory Vesicle LumenCytoplasmic VesicleSecretory VesicleChromaffin Granule LumenSecretory Vesicle MembraneSingle-Pass Type Ii Membrane ProteinChromaffin Granule Membrane |
| Alternative Antibody Names | Anti-Dopamine Beta-Hydroxylase antibodyAnti-Dopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase antibodyAnti-Dbh antibody |
Information sourced from Uniprot.org