Anti-DOK7 antibody (10-59 aa) (STJ92766)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human DOK7 at the amino acid range 10-59
General Information
| Short Description | Rabbit polyclonal anti-Protein Dok-7 (10-59 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DOK7 |
| Gene ID | 285489 |
| Uniprot ID | DOK7_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human DOK7 at the amino acid range 10-59 |
| Immunogen Region | 10-59 aa |
| Specificity | Dok-7 Polyclonal Antibody detects endogenous levels of Dok-7 protein. |
Additional Info
| Function | Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK. |
| Protein Name | Protein Dok-7Downstream Of Tyrosine Kinase 7 |
| Database Links | |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSynapseAccumulates At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Protein Dok-7 antibodyAnti-Downstream Of Tyrosine Kinase 7 antibodyAnti-DOK7 antibodyAnti-C4orf25 antibody |
Information sourced from Uniprot.org