| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein Dok-7 (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DOK7 |
| Gene ID: |
285489 |
| Uniprot ID: |
DOK7_HUMAN |
| Immunogen Region: |
10-59 aa |
| Specificity: |
Dok-7 Polyclonal Antibody detects endogenous levels of Dok-7 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human DOK7 at the amino acid range 10-59 |
| Function | Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK. |
| Protein Name | Protein Dok-7Downstream Of Tyrosine Kinase 7 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSynapseAccumulates At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Protein Dok-7 antibodyAnti-Downstream Of Tyrosine Kinase 7 antibodyAnti-DOK7 antibodyAnti-C4orf25 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
