• Western blot analysis of lysates from 293 and mouse lung, using DOK4 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Dok-4 Polyclonal Antibody

Anti-DOK4 antibody (11-60 aa) (STJ92763)

SKU:
STJ92763

€57.50 - €282.50
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Docking protein 4 (11-60 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DOK4
Gene ID: 55715
Uniprot ID: DOK4_HUMAN
Immunogen Region: 11-60 aa
Specificity: Dok-4 Polyclonal Antibody detects endogenous levels of Dok-4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human DOK4 at the amino acid range 11-60
Post Translational Modifications Phosphorylated on tyrosine residues in response to insulin, IGF1 or RET stimulation.
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
Protein Name Docking Protein 4
Downstream Of Tyrosine Kinase 4
Insulin Receptor Substrate 5
Irs-5
Irs5
Database Links Reactome: R-HSA-8853659
Alternative Antibody Names Anti-Docking Protein 4 antibody
Anti-Downstream Of Tyrosine Kinase 4 antibody
Anti-Insulin Receptor Substrate 5 antibody
Anti-Irs-5 antibody
Anti-Irs5 antibody
Anti-DOK4 antibody

Information sourced from Uniprot.org

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