| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-DOG-1 is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
K9 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2b |
| Formulation: |
Tissue culture supernatant with Sodium azide |
| Concentration: |
>=12 mg/L |
| Dilution Range: |
IHC-P 1:50 |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Immunogen: |
Prokaryotic recombinant protein corresponding to part of the C-terminus of the cytoplasmic domain of the human DOG-1 molecule. |
| Background | DOG-1, a 986 amino acid protein of unknown function, is expressed predominantly on the plasma membrane of gastrointestinal stromal tumors (GISTs) and is rarely expressed in other soft tissue tumors, which, due to appearance, can be confused with GISTs. Reactivity for DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express KIT antigen. The use of PBS-based diluents may result in increased background staining. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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