Anti-DOG1 antibody [K9] (STJ16101727)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenProkaryotic recombinant protein corresponding to part of the C-terminus of the cytoplasmic domain of the human DOG-1 molecule.
STJ16101727-1
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General Information

Short DescriptionMouse monoclonal anti-DOG-1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDK9
IsotypeIgG2b
ConjugationUnconjugated
Concentration>=12 mg/L
Dilution RangeIHC-P 1:50
FormulationTissue culture supernatant with Sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

ImmunogenProkaryotic recombinant protein corresponding to part of the C-terminus of the cytoplasmic domain of the human DOG-1 molecule.

Additional Info

Background DOG-1, a 986 amino acid protein of unknown function, is expressed predominantly on the plasma membrane of gastrointestinal stromal tumors (GISTs) and is rarely expressed in other soft tissue tumors, which, due to appearance, can be confused with GISTs. Reactivity for DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express KIT antigen. The use of PBS-based diluents may result in increased background staining.

Information sourced from Uniprot.org

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