Anti-DOCK6 antibody (1460-1510 aa) (STJ197944)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human DOCK6 at the amino acid range 1460-1510
General Information
| Short Description | Rabbit polyclonal anti-Dedicator of cytokinesis protein 6 (1460-1510 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DOCK6 |
| Gene ID | 57572 |
| Uniprot ID | DOCK6_HUMAN |
| Immunogen | Synthesized peptide derived from the human DOCK6 at the amino acid range 1460-1510 |
| Immunogen Region | 1460-1510 aa |
| Specificity | This antibody detects endogenous levels of human DOCK6 |
Additional Info
| Function | Acts as a guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth. |
| Protein Name | Dedicator Of Cytokinesis Protein 6 |
| Database Links | Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-983231 |
| Cellular Localisation | CytoplasmPerinuclear RegionMainly Located Near The Cell Surface |
| Alternative Antibody Names | Anti-Dedicator Of Cytokinesis Protein 6 antibodyAnti-DOCK6 antibodyAnti-KIAA1395 antibody |
Information sourced from Uniprot.org