| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Dynamin-binding protein (940-990 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNMBP |
| Gene ID: |
23268 |
| Uniprot ID: |
DNMBP_HUMAN |
| Immunogen Region: |
940-990 aa |
| Specificity: |
DNMBP Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein at the amino acid range 940-990 |
| Function | Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi. |
| Protein Name | Dynamin-Binding ProteinScaffold Protein Tuba |
| Database Links | Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmGolgi ApparatusGolgi StackCytoskeletonSynapseCell JunctionLocalizes To The Apical JunctionColocalizes With Tjp1 |
| Alternative Antibody Names | Anti-Dynamin-Binding Protein antibodyAnti-Scaffold Protein Tuba antibodyAnti-DNMBP antibodyAnti-ARHGEF36 antibodyAnti-KIAA1010 antibodyAnti-TUBA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
