Anti-DNMBP antibody (940-990 aa) (STJ192927)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein at the amino acid range 940-990
STJ192927
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General Information

Short DescriptionRabbit polyclonal anti-Dynamin-binding protein (940-990 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolDNMBP
Gene ID23268
Uniprot IDDNMBP_HUMAN
ImmunogenSynthesized peptide derived from part of the human protein at the amino acid range 940-990
Immunogen Region940-990 aa
SpecificityDNMBP Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Function Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi.
Protein Name Dynamin-Binding Protein
Scaffold Protein Tuba
Database Links Reactome: R-HSA-9013148
Cellular Localisation Cytoplasm
Golgi Apparatus
Golgi Stack
Cytoskeleton
Synapse
Cell Junction
Localizes To The Apical Junction
Colocalizes With Tjp1
Alternative Antibody Names Anti-Dynamin-Binding Protein antibody
Anti-Scaffold Protein Tuba antibody
Anti-DNMBP antibody
Anti-ARHGEF36 antibody
Anti-KIAA1010 antibody
Anti-TUBA antibody

Information sourced from Uniprot.org

Citations

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