• Western blot analysis of extracts of mouse testis, using DNAL1 antibody (STJ110566) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Immunofluorescence analysis of U2OS cells using DNAL1 antibody (STJ110566) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of U2OS cells using DNAL1 antibody (STJ110566) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of mouse testis, using DNAL1 antibody (STJ110566) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-DNAL1 antibody (41-190) (STJ110566)

SKU:
STJ110566

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DNAL1 (41-190) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DNAL1
Gene ID: 83544
Uniprot ID: DNAL1_HUMAN
Immunogen Region: 41-190
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 41-190 of human DNAL1 (NP_113615.2).
Immunogen Sequence: DASLSMLANCEKLSLSTNCI EKIANLNGLKNLRILSLGRN NIKNLNGLEAVGDTLEELWI SYNFIEKLKGIHIMKKLKIL YMSNNLVKDWAEFVKLAELP CLEDLVFVGNPLEEKHSAEN NWIEEATKRVPKLKKLDGTP VIKGDEEEDN
Tissue Specificity Expressed in tissues carrying motile cilia such as respiratory epithelia, ependyma and testis.
Function Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency. Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme. Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry.
Protein Name Dynein Axonemal Light Chain 1
Lc1
Cellular Localisation Cytoplasm
Cytoskeleton
Cilium Axoneme
Alternative Antibody Names Anti-Dynein Axonemal Light Chain 1 antibody
Anti-Lc1 antibody
Anti-DNAL1 antibody
Anti-C14orf168 antibody

Information sourced from Uniprot.org

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