• Western blot analysis of lysates from HeLa, HepG2, and MCF-7 cells, using DNAL1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Western blot analysis of various cells using Dynein LC 1 Polyclonal Antibody diluted at 1:500

Anti-DNAL1 antibody (121-170 aa) (STJ92796)

SKU:
STJ92796

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dynein axonemal light chain 1 (121-170 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DNAL1
Gene ID: 83544
Uniprot ID: DNAL1_HUMAN
Immunogen Region: 121-170 aa
Specificity: Dynein LC 1 Polyclonal Antibody detects endogenous levels of Dynein LC 1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human DNAL1 at the amino acid range 121-170
Function Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency. Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme. Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry.
Protein Name Dynein Axonemal Light Chain 1
Lc1
Cellular Localisation Cytoplasm
Cytoskeleton
Cilium Axoneme
Alternative Antibody Names Anti-Dynein Axonemal Light Chain 1 antibody
Anti-Lc1 antibody
Anti-DNAL1 antibody
Anti-C14orf168 antibody

Information sourced from Uniprot.org

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