Anti-DNAJC9 antibody (STJA0008213)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human DNAJC9
General Information
| Short Description | Rabbit polyclonal anti-DnaJ homolog subfamily C member 9 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DNAJC9 |
| Gene ID | 23234 |
| Uniprot ID | DNJC9_HUMAN |
| Immunogen | Synthesized peptide derived from human DNAJC9 |
| Specificity | This antibody detects endogenous levels of DNAJC9 at Human, Mouse |
Additional Info
| Function | Acts as a dual histone chaperone and heat shock co-chaperone. As a histone chaperone, forms a co-chaperone complex with MCM2 and histone H3-H4 heterodimers.and may thereby assist MCM2 in histone H3-H4 heterodimer recognition and facilitate the assembly of histones into nucleosomes. May also act as a histone co-chaperone together with TONSL. May recruit histone chaperones ASF1A, NASP and SPT2 to histone H3-H4 heterodimers. Also plays a role as co-chaperone of the HSP70 family of molecular chaperone proteins, such as HSPA1A, HSPA1B and HSPA8. As a co-chaperone, may play a role in the recruitment of HSP70-type molecular chaperone machinery to histone H3-H4 substrates, thereby maintaining the histone structural integrity. Exhibits activity to assemble histones onto DNA in vitro. |
| Protein Name | Dnaj Homolog Subfamily C Member 9Hdjc9Dnaj Protein Sb73 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCell MembranePredominantly NuclearTranslocates To The Cytoplasm And Membrane After Heat Shock |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 9 antibodyAnti-Hdjc9 antibodyAnti-Dnaj Protein Sb73 antibodyAnti-DNAJC9 antibody |
Information sourced from Uniprot.org