Anti-DNAJC9 antibody (1-260) (STJ115142)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DNAJC9 (1-260) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DNAJC9 |
| Gene ID | 23234 |
| Uniprot ID | DNJC9_HUMAN |
| Immunogen Region | 1-260 |
| Immunogen Sequence | MGLLDLCEEVFGTADLYRVL GVRREASDGEVRRGYHKVSL QVHPDRVGEGDKEDATRRFQ ILGKVYSVLSDREQRAVYDE QGTVDEDSPVLTQDRDWEAY WRLLFKKISLEDIQAFEKTY KGSEEELADIKQAYLDFKGD MDQIMESVLCVQYTEEPRIR NIIQQAIDAGEVPSYNAFVK ESKQKMNARKRRAQEEAKEA EMSRKELGLDEGVDSLKAAI QSRQKDRQKEMDNFLAQME |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DNAJC9 (NP_056005.1). |
Additional Info
| Tissue Specificity | Expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, thymus, ovary, colon and peripheral blood. |
| Function | Acts as a dual histone chaperone and heat shock co-chaperone. As a histone chaperone, forms a co-chaperone complex with MCM2 and histone H3-H4 heterodimers.and may thereby assist MCM2 in histone H3-H4 heterodimer recognition and facilitate the assembly of histones into nucleosomes. May also act as a histone co-chaperone together with TONSL. May recruit histone chaperones ASF1A, NASP and SPT2 to histone H3-H4 heterodimers. Also plays a role as co-chaperone of the HSP70 family of molecular chaperone proteins, such as HSPA1A, HSPA1B and HSPA8. As a co-chaperone, may play a role in the recruitment of HSP70-type molecular chaperone machinery to histone H3-H4 substrates, thereby maintaining the histone structural integrity. Exhibits activity to assemble histones onto DNA in vitro. |
| Protein Name | Dnaj Homolog Subfamily C Member 9Hdjc9Dnaj Protein Sb73 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCell MembranePredominantly NuclearTranslocates To The Cytoplasm And Membrane After Heat Shock |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 9 antibodyAnti-Hdjc9 antibodyAnti-Dnaj Protein Sb73 antibodyAnti-DNAJC9 antibody |
Information sourced from Uniprot.org