| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DNAJC9 (1-260) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNAJC9 |
| Gene ID: |
23234 |
| Uniprot ID: |
DNJC9_HUMAN |
| Immunogen Region: |
1-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DNAJC9 (NP_056005.1). |
| Immunogen Sequence: |
MGLLDLCEEVFGTADLYRVL GVRREASDGEVRRGYHKVSL QVHPDRVGEGDKEDATRRFQ ILGKVYSVLSDREQRAVYDE QGTVDEDSPVLTQDRDWEAY WRLLFKKISLEDIQAFEKTY KGSEEELADIKQAYLDFKGD MDQIMESVLCVQYTEEPRIR NIIQQAIDAGEVPSYNAFVK ESKQKMNARKRRAQEEAKEA EMSRKELGLDEGVDSLKAAI QSRQKDRQKEMDNFLAQME |
| Tissue Specificity | Expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, thymus, ovary, colon and peripheral blood. |
| Function | Acts as a dual histone chaperone and heat shock co-chaperone. As a histone chaperone, forms a co-chaperone complex with MCM2 and histone H3-H4 heterodimers.and may thereby assist MCM2 in histone H3-H4 heterodimer recognition and facilitate the assembly of histones into nucleosomes. May also act as a histone co-chaperone together with TONSL. May recruit histone chaperones ASF1A, NASP and SPT2 to histone H3-H4 heterodimers. Also plays a role as co-chaperone of the HSP70 family of molecular chaperone proteins, such as HSPA1A, HSPA1B and HSPA8. As a co-chaperone, may play a role in the recruitment of HSP70-type molecular chaperone machinery to histone H3-H4 substrates, thereby maintaining the histone structural integrity. Exhibits activity to assemble histones onto DNA in vitro. |
| Protein Name | Dnaj Homolog Subfamily C Member 9Hdjc9Dnaj Protein Sb73 |
| Cellular Localisation | NucleusCytoplasmCell MembranePredominantly NuclearTranslocates To The Cytoplasm And Membrane After Heat Shock |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 9 antibodyAnti-Hdjc9 antibodyAnti-Dnaj Protein Sb73 antibodyAnti-DNAJC9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
