Anti-DNAJC7 antibody (230-380) (STJ23402)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DNAJC7 (230-380) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DNAJC7 |
| Gene ID | 7266 |
| Uniprot ID | DNJC7_HUMAN |
| Immunogen Region | 230-380 |
| Immunogen Sequence | VQFFVQALRMAPDHEKACIA CRNAKALKAKKEDGNKAFKE GNYKLAYELYTEALGIDPNN IKTNAKLYCNRGTVNSKLRK LDDAIEDCTNAVKLDDTYIK AYLRRAQCYMDTEQYEEAVR DYEKVYQTEKTKEHKQLLKN AQLELKKSKRK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human DNAJC7 (NP_003306.3). |
Additional Info
| Function | Acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm. |
| Protein Name | Dnaj Homolog Subfamily C Member 7Tetratricopeptide Repeat Protein 2Tpr Repeat Protein 2 |
| Database Links | Reactome: R-HSA-3371453 |
| Cellular Localisation | CytoplasmNucleusCytoskeletonColocalizes With Nr1i3 To Microtubules |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 7 antibodyAnti-Tetratricopeptide Repeat Protein 2 antibodyAnti-Tpr Repeat Protein 2 antibodyAnti-DNAJC7 antibodyAnti-TPR2 antibodyAnti-TTC2 antibody |
Information sourced from Uniprot.org