Anti-DNAH8 antibody (1738-1749) (STJ72340)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DNAH8 (1738-1749) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Not yet tested-our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 515kDa according to NP_001362.2. Therefore we canno |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DNAH8 |
| Gene ID | 1769 |
| Uniprot ID | DYH8_HUMAN |
| Accession Number | NP_001362.2 |
| Immunogen Region | 1738-1749 |
| Immunogen Sequence | SQTTHDLSKFDR |
Additional Info
| Function | Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility.implicated in sperm flagellar assembly. |
| Protein Name | Dynein Axonemal Heavy Chain 8Axonemal Beta Dynein Heavy Chain 8Ciliary Dynein Heavy Chain 8 |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum AxonemeDetected In Sperm TailWith Almost Exclusive Localization To The Principal PieceAlso Detected In The Cytoplasm Of Primary Spermatocytes |
| Alternative Antibody Names | Anti-Dynein Axonemal Heavy Chain 8 antibodyAnti-Axonemal Beta Dynein Heavy Chain 8 antibodyAnti-Ciliary Dynein Heavy Chain 8 antibodyAnti-DNAH8 antibody |
Information sourced from Uniprot.org