Anti-DNA Nucleotidylexotransferase antibody [R08-8D9] (STJA0034921)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human TdT
General Information
| Short Description | Rabbit monoclonal anti-DNA Nucleotidylexotransferase for use in WB and IP in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-8D9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DNTT |
| Gene ID | 1791 |
| Uniprot ID | TDT_HUMAN |
| Immunogen | A synthetic peptide of human TdT |
Additional Info
| Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
| Protein Name | Dna NucleotidylexotransferaseTerminal Addition EnzymeTerminal DeoxynucleotidyltransferaseTerminal Transferase |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Nucleotidylexotransferase antibodyAnti-Terminal Addition Enzyme antibodyAnti-Terminal Deoxynucleotidyltransferase antibodyAnti-Terminal Transferase antibodyAnti-DNTT antibodyAnti-TDT antibody |
Information sourced from Uniprot.org