• STJ73007 (1µg/ml) staining of Human Lung lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-DMTF1-Isoform a antibody (N-Term) (STJ73007)

SKU:
STJ73007-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-DMTF1-Isoform a (N-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:16000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: DMTF1
Gene ID: 9988
Uniprot ID: DMTF1_HUMAN
Immunogen Region: N-Term
Accession Number: NP_066968.3; NP_001135798.1
Specificity: This antibody is expected to recognize both reported isoform a (NP_066968.3) only. Reported variants represent identical protein: NP_066968.3, NP_001135799.1
Immunogen Sequence: CPQNEADEIDSEDS
Post Translational Modifications Phosphorylated by the cyclin-D2/CDK4, cyclin-D3/CDK4 and cyclin-D2/CDK6 complexes and to a lesser extent by the cyclin-D1/CDK4 complex.
Function Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest. Binds to the consensus sequence 5'-CCCGGTATGT-3'. Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene. Isoform 2 may antagonize transcriptional activation by isoform 1.
Protein Name Cyclin-D-Binding Myb-Like Transcription Factor 1
Hdmtf1
Cyclin-D-Interacting Myb-Like Protein 1
Hdmp1
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Cyclin-D-Binding Myb-Like Transcription Factor 1 antibody
Anti-Hdmtf1 antibody
Anti-Cyclin-D-Interacting Myb-Like Protein 1 antibody
Anti-Hdmp1 antibody
Anti-DMTF1 antibody
Anti-DMP1 antibody

Information sourced from Uniprot.org

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