Anti-DMC1 antibody (1-260) (STJ23393)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DMC1 (1-260) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DMC1 |
| Gene ID | 11144 |
| Uniprot ID | DMC1_HUMAN |
| Immunogen Region | 1-260 |
| Immunogen Sequence | MKEDQVVAEEPGFQDEEESL FQDIDLLQKHGINVADIKKL KSVGICTIKGIQMTTRRALC NVKGLSEAKVDKIKEAANKL IEPGFLTAFEYSEKRKMVFH ITTGSQEFDKLLGGGIESMA ITEAFGEFRTGKTQLSHTLC VTAQLPGAGGYPGGKIIFID TENTFRPDRLRDIADRFNVD HDAVLDNVLYARAYTSEHQM ELLDYVAAKFHEEAGIFKLL IIDSIMALFRVDFSGRGEL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DMC1 (NP_008999.2). |
Additional Info
| Function | Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. |
| Protein Name | Meiotic Recombination Protein Dmc1/Lim15 Homolog |
| Database Links | Reactome: R-HSA-912446 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Meiotic Recombination Protein Dmc1/Lim15 Homolog antibodyAnti-DMC1 antibodyAnti-DMC1H antibodyAnti-LIM15 antibody |
Information sourced from Uniprot.org