Anti-DLAT antibody [4A4-B6-C10] (STJ99150)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant human Pyruvate Dehydrogenase E2 protein fragments expressed in E.coli.
General Information
| Short Description | Mouse monoclonal anti-Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial for use in WB, ICC and IP in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagent |
| Applications | WB/ICC/IP |
| Host | Mouse |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 4A4-B6-C10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000ICC 1:300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DLAT |
| Gene ID | 1737 |
| Uniprot ID | ODP2_HUMAN |
| Immunogen | Purified recombinant human Pyruvate Dehydrogenase E2 protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of Pyruvate Dehydrogenase E2 and does not cross-react with related proteins. |
Additional Info
| Function | As part of the pyruvate dehydrogenase complex, catalyzes the transfers of an acetyl group to a lipoic acid moiety (Probable). The pyruvate dehydrogenase complex, catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links cytoplasmic glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle (Probable). |
| Protein Name | Dihydrolipoyllysine-Residue Acetyltransferase Component Of Pyruvate Dehydrogenase Complex - Mitochondrial70 Kda Mitochondrial Autoantigen Of Primary Biliary CirrhosisPbcDihydrolipoamide Acetyltransferase Component Of Pyruvate Dehydrogenase ComplexM2 Antigen Complex 70 Kda SubunitPyruvate Dehydrogenase Complex Component E2Pdc-E2Pdce2 |
| Database Links | Reactome: R-HSA-204174Reactome: R-HSA-5362517Reactome: R-HSA-9857492Reactome: R-HSA-9861559 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Dihydrolipoyllysine-Residue Acetyltransferase Component Of Pyruvate Dehydrogenase Complex - Mitochondrial antibodyAnti-70 Kda Mitochondrial Autoantigen Of Primary Biliary Cirrhosis antibodyAnti-Pbc antibodyAnti-Dihydrolipoamide Acetyltransferase Component Of Pyruvate Dehydrogenase Complex antibodyAnti-M2 Antigen Complex 70 Kda Subunit antibodyAnti-Pyruvate Dehydrogenase Complex Component E2 antibodyAnti-Pdc-E2 antibodyAnti-Pdce2 antibodyAnti-DLAT antibodyAnti-DLTA antibody |
Information sourced from Uniprot.org