Anti-DHX37 antibody (STJA0009748)

SKU:
STJA0009748

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Probable ATP-dependent RNA helicase DHX37 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DHX37
Gene ID: 57647
Uniprot ID: DHX37_HUMAN
Specificity: This antibody detects endogenous levels of DHX37 at Human
Immunogen: Synthesized peptide derived from human DHX37
Function ATP-binding RNA helicase that plays a role in maturation of the small ribosomal subunit in ribosome biogenesis. Required for the release of the U3 snoRNP from pre-ribosomal particles. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Plays a role in early testis development. Probably also plays a role in brain development.
Protein Name Probable Atp-Dependent Rna Helicase Dhx37
Deah Box Protein 37
Database Links Reactome: R-HSA-6790901
Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Cytoplasm
Nucleus Membrane
Alternative Antibody Names Anti-Probable Atp-Dependent Rna Helicase Dhx37 antibody
Anti-Deah Box Protein 37 antibody
Anti-DHX37 antibody
Anti-DDX37 antibody
Anti-KIAA1517 antibody

Information sourced from Uniprot.org

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