Anti-DHRSX antibody (STJA0004596)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human DHRSX
General Information
| Short Description | Rabbit polyclonal anti-Dehydrogenase/Reductase Sdr Family Member On Chromosome X for use in WB, IHC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | WB 1:500-1:2000, IHC 1:25-1:100 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | DHRSX |
| Gene ID | 207063 |
| Uniprot ID | DHRSX_HUMAN |
| Immunogen | Fusion protein of human DHRSX |
Additional Info
| Tissue Specificity | Widely expressed. Highly expressed in the pancreas. |
| Function | Oxidoreductase that plays a key role in early steps of protein N-linked glycosylation by mediating two non-consecutive steps in dolichol biosynthesis. Acts both as a NAD(+)-dependent dehydrogenase and as a NADPH-dependent reductase during the conversion of polyprenol into dolichol. First catalyzes the NAD(+)-dependent dehydrogenation of polyprenol into polyprenal.polyprenal is then reduced into dolichal by SRD5A3. It then catalyzes the NADPH-dependent reduction of dolichal into dolichol. May also acts as a positive regulator of starvation-induced autophagy. |
| Protein Name | Polyprenol DehydrogenaseDhrsxyDehydrogenase/Reductase Sdr Family Member On Chromosome XDolichal Reductase |
| Database Links | |
| Cellular Localisation | Lipid DropletSecretedSecreted In A Non-Classical FormA Signal Peptide Sequence At Position 1-31 Is Predicted |
| Alternative Antibody Names | Anti-Polyprenol Dehydrogenase antibodyAnti-Dhrsxy antibodyAnti-Dehydrogenase/Reductase Sdr Family Member On Chromosome X antibodyAnti-Dolichal Reductase antibodyAnti-DHRSX antibodyAnti-CXorf11 antibodyAnti-DHRS5X antibodyAnti-SDR46C1 antibodyAnti-SDR7C6 antibodyAnti-UNQ6508 antibodyAnti-PRO21433 antibody |
Information sourced from Uniprot.org