STJ71113 (3µg/ml) staining of paraffin embedded Human Liver. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

Anti-DGAT2 antibody (Internal) (STJ71113)

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STJ71113-100
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Host: Goat
Applications: Pep-ELISA/IHC/FC
Reactivity: Human/Mouse/Rat/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-DGAT2 (Internal) is suitable for use in ELISA, Immunohistochemistry and Flow Cytometry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:128000.
IHC: In paraffin embedded Human Liver shows granular cytoplasm staining of hepatocytes. Recommended concentration: 3µg/ml.
FC:Flow cytometric analysis of HeLa cells. Recommended conce
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: DGAT2
Gene ID: 84649
Uniprot ID: DGAT2_HUMAN
Immunogen Region: Internal
Accession Number: NP_115953.2; NP_001240820.1
Specificity: This antibody is not expected to cross-react with other DGAT members.
Immunogen Sequence: KLEHPTQQDIDLYH
Function Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides. Functions also as an acyl-CoA retinol acyltransferase (ARAT). Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG).
Protein Name Diacylglycerol O-Acyltransferase 2
Acyl-Coa Retinol O-Fatty-Acyltransferase
Arat
Retinol O-Fatty-Acyltransferase
Diglyceride Acyltransferase 2
Database Links Reactome: R-HSA-1482883
Reactome: R-HSA-75109
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Lipid Droplet
Cytoplasm
Perinuclear Region
Alternative Antibody Names Anti-Diacylglycerol O-Acyltransferase 2 antibody
Anti-Acyl-Coa Retinol O-Fatty-Acyltransferase antibody
Anti-Arat antibody
Anti-Retinol O-Fatty-Acyltransferase antibody
Anti-Diglyceride Acyltransferase 2 antibody
Anti-DGAT2 antibody
Anti-HMFN1045 antibody
Anti-UNQ738 antibody
Anti-PRO1433 antibody

Information sourced from Uniprot.org

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