Anti-DET1 antibody (48-98 aa) (STJ195403)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human DET1 at the amino acid range 48-98
General Information
| Short Description | Rabbit polyclonal anti-DET1 homolog (48-98 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DET1 |
| Gene ID | 55070 |
| Uniprot ID | DET1_HUMAN |
| Immunogen | Synthesized peptide derived from the human DET1 at the amino acid range 48-98 |
| Immunogen Region | 48-98 aa |
| Specificity | This antibody detects endogenous levels of DET1 at Human/Mouse |
Additional Info
| Function | Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation. |
| Protein Name | Det1 HomologDe-Etiolated-1 Homolog |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Det1 Homolog antibodyAnti-De-Etiolated-1 Homolog antibodyAnti-DET1 antibody |
Information sourced from Uniprot.org