| Host: |
Rabbit |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Desmoglein-3 (379-491aa) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ZR128 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: |
Affinity purified |
| Dilution Range: |
1:100-200 |
| Storage Instruction: |
Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: |
DSG3 |
| Gene ID: |
1830 |
| Uniprot ID: |
DSG3_HUMAN |
| Immunogen Region: |
379-491aa |
| Specificity: |
Positive Control: Squamous cell carcinoma |
| Immunogen: |
Recombinant fragment (around aa 379-491) human DSG3 protein |
| Tissue Specificity | Epidermis, tongue, tonsil, esophagus and carcinomas. Expressed in skin and mucosa (at protein level). |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Protein Name | Desmoglein-3130 Kda Pemphigus Vulgaris AntigenPvaCadherin Family Member 6 |
| Database Links | Reactome: R-HSA-351906Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
| Alternative Antibody Names | Anti-Desmoglein-3 antibodyAnti-130 Kda Pemphigus Vulgaris Antigen antibodyAnti-Pva antibodyAnti-Cadherin Family Member 6 antibodyAnti-DSG3 antibodyAnti-CDHF6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
