Anti-Desmoglein 1 antibody [R07-2K4] (STJA0035731)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human DSG1
General Information
| Short Description | Rabbit monoclonal anti-Desmoglein 1 for use in WB, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R07-2K4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DSG1 |
| Gene ID | 1828 |
| Uniprot ID | DSG1_HUMAN |
| Immunogen | A synthesized peptide derived from human DSG1 |
Additional Info
| Tissue Specificity | Expressed in all suprabasal layers of the epidermis, with the highest expression seen in the granular layer (at protein level). |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Protein Name | Desmoglein-1Cadherin Family Member 4Desmosomal Glycoprotein 1Dg1DgiPemphigus Foliaceus Antigen |
| Database Links | Reactome: R-HSA-351906Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9696264Reactome: R-HSA-9696270 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosomeCytoplasmNucleus |
| Alternative Antibody Names | Anti-Desmoglein-1 antibodyAnti-Cadherin Family Member 4 antibodyAnti-Desmosomal Glycoprotein 1 antibodyAnti-Dg1 antibodyAnti-Dgi antibodyAnti-Pemphigus Foliaceus Antigen antibodyAnti-DSG1 antibodyAnti-CDHF4 antibody |
Information sourced from Uniprot.org