Anti-DENTT/CDA1 antibody (C-Term) (STJ70085)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DENTT/CDA1 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.IHC: In paraffin embedded Human Testis shows nucleolar staining in spermatocytes. Recommended concentration, 5-10µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TSPYL2 |
| Gene ID | 64061 |
| Uniprot ID | TSYL2_HUMAN |
| Accession Number | NP_071400.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | PNGWANPGKRGKTG |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. |
| Function | Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
| Protein Name | Testis-Specific Y-Encoded-Like Protein 2Tspy-Like Protein 2Cell Division Autoantigen 1Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4Ctcl-Associated Antigen Se20-4Differentially-Expressed Nucleolar Tgf-Beta1 Target ProteinNuclear Protein Of 79 KdaNp79 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | NucleusCytoplasmEnriched In Transcriptionally Active Regions Of Chromatin In Neurons |
| Alternative Antibody Names | Anti-Testis-Specific Y-Encoded-Like Protein 2 antibodyAnti-Tspy-Like Protein 2 antibodyAnti-Cell Division Autoantigen 1 antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4 antibodyAnti-Ctcl-Associated Antigen Se20-4 antibodyAnti-Differentially-Expressed Nucleolar Tgf-Beta1 Target Protein antibodyAnti-Nuclear Protein Of 79 Kda antibodyAnti-Np79 antibodyAnti-TSPYL2 antibodyAnti-CDA1 antibodyAnti-DENTT antibodyAnti-TSPX antibodyAnti-HRIHFB2216 antibody |
Information sourced from Uniprot.org